This initiative focuses on mitigating the impact of
parasitic infections in the U.S. by addressing Chagas disease complications,
detecting soil-transmitted helminths, and enhancing public awareness of
parasitic diseases through evidence-based prevention and control strategies.

This NOFO has three components. You may apply for one
component. Each component has its own outcomes and approach as follows.

Component A: Chagas disease

This NOFO aims to:

• Educate public health partners to recognize and diagnose
  Chagas disease.
• 
  
  Support the Division of Parasitic Disease and Malaria (DPDM)
  strategic goal of reducing deaths, illnesses, and disabilities caused by
  parasitic diseases in the United States.

The approach for this component includes:

• Create and share educational materials, prevention
  strategies, and community-level recommendations to lower illness and death from
  Chagas disease, in the U.S.

 Component B: Soil-transmitted helminths

This NOFO aims to:

• Confirm whether STH infections are still present in
  historically endemic areas.
• 
  
  Identify risk factors for STH infection.
•  Develop and implement prevention and control measures to
  stop STH infections.

Expected outcomes include:

• Updated data on STH prevalence.
• 
  
  Increased awareness of these infections in communities and
  among HCPs.
• 
  
  Stronger local capacity in health departments and healthcare
  centers to detect, prevent, and manage STH infections.

The approach for this component includes:

• Identify areas at risk for STH infections in the
  Southeastern U.S. (this includes states in the South region, as defined by the
  U.S. Census Bureau, except for areas of Alabama and Mississippi where work was
  previously completed). Determine whether these infections are still prevalent
  and implement control strategies.

 Component C: Other parasitic diseases of domestic concern

This NOFO aims to improve the ability of health departments
and healthcare providers to identify, treat, control, and prevent parasitic
diseases of domestic concern in their areas.

The approach for this component includes:

• Develop and disseminate educational materials,
  community-level prevention and control recommendations, and strategies to
  reduce morbidity and mortality due to other parasitic diseases of domestic
  concern in the United States.