The Mark Foundation Endeavor Awards support collaborative
research projects that bring together investigators with diverse areas of
expertise to tackle challenges in the prevention, diagnosis, and treatment of
cancer. These grants are awarded to teams of three or more investigators to
generate and integrate data from diverse lines of research and transform those
insights into advances for cancer patients that could not be achieved by
individual efforts.

Endeavor Awards are $3,000,000, disbursed over a 3-year
term.

Investigator Eligibility:

• There are no restrictions on citizenship or geography.
• 
  
  Applicants must have an independent faculty appointment
  (tenure-track or equivalent) at a non-profit academic institution.
• 
  
  Investigators may be co-PI or collaborator on more than
  one proposal but may only serve as Principal Investigator on one proposal.
• 
  
  Investigators who are currently a co-PI on an Endeavor
  team are permitted to apply as co-PI or collaborator on a new application.

Project Eligibility:

• Basic, translational, and clinical projects are eligible.
• 
  
  The project must seek to address an overarching, urgent
  scientific question.
• 
  
  Sub-projects should be designed to elucidate various
  aspects of the overarching question, theme, or focus.
• 
  
  The output of the individual team members (data, samples,
  hypotheses, compounds, etc.) must be integrated and/or shared in a way that
  makes the impact of the project as a whole larger than the sum of its parts.
• 
  
  Proposed projects must not be supported by other sources
  of funding. Finalists will be asked to discuss any potential overlap with other
  current or pending awards.

Team Composition:

• Teams must be composed of one PI, and between 2-8 co-PIs
  (see “Team Roles” section for definitions).
• 
  
  Inter-institutional collaborations are permitted and
  encouraged.
• 
  
  Teams are encouraged to consider diversity in terms of
  discipline, seniority, gender, race, ethnicity, and any other parameters that
  will enhance the team’s ability to approach challenging problems from fresh
  perspectives.
• 
  
  The Mark Foundation for Cancer Research does not
  discriminate on the basis of race, color, religion, national origin, sex,
  gender identity, sexual orientation, age, disability, or any other legally
  protected characteristics.